A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Samuel, Joice
- Study on Determinants of Self Medication Practice amongst Consumers in Parts of East Bengaluru
Authors
1 Department of Pharmacy Practice, Krupanidhi College of Pharmacy, Bengaluru, IN
2 Krupanidhi College of Pharmacy, Bengaluru, IN
3 Department of Community Medicine, MVJ Medical College and Research Hospital, Bengaluru, IN
Source
Journal of Pharmaceutical Research, Vol 14, No Special Ed (2015), Pagination: 56-56Abstract
INTRODUCTION: Self medication is the problem that has the potential to harm society due to irrational use of drugs. The nature and extend of practice of self medication depends upon many factors like nature of the disease, educational qualification of the person, non availability of the specialized person, cultural and social influences.AIM: To identify the socio demographic determinants associated with selfmedication practice in the population of selected area.
METHODOLOGY: A community based cross sectional study was conducted in East Bengaluru area over the period of 6 months using pre tested semi structured questionnaire.The subjects were asked to recollect self medication practice for one year recall period.
RESULTS& DISCUSSION: The data on socio demographic characteristics and practice of self medication were collected from 427 study participants. A significant correlation was observed particular age group ( 24 - 30 years)[Prob>F = 0.0056, Prob>|t| = <0.0001]; while a moderate correlation for education[Prob>|t| = <0.0001], occupation [Prob>|t| = <0.0001] and economic status[Prob>|t| = <0.0001] of the survey respondents. And no particular correlation was observed for gender, familial types and the area of domicile of the participants.
The frequency of self medication use ranged from minimum of one time to all the time.Fever (68.67%), pain (54.56%), and cough (42.15%) were the most common illnesses where self-medication is common. Pain killers (68.85%) and antipyretics (50.58%) were the most commonly used self medicating drugs. Telling the symptoms to pharmacist (89.69%) was the commonest method adopted to procure drugs by the users. The major reason for self medication was lack of time to visit doctor (32.31). Only 33.34% of the subjects agree self medication is harmful; but most of them (66.97%) did not advise others to use self-medication drugs.
CONCLUSION: Self medication is more prevalent among the younger population of the respondents, irrespective of their educational backgrounds andeconomic status. A newer approach to connect with andeducating these consumers is essential.
Keywords
Self Medication, Community Pharmacist, OTC Medications.- Case Series on Hemoglobin E-Beta-Thalassemia Major
Authors
1 Krupanidhi College of Pharmacy, 12/1 Chikka Bellandur, Carmelaram Post, Varthur Hobli, Bangalore - 560 035, Karnataka, IN
2 Krupanidhi College of Pharmacy, 12/1 Chikka Bellandur, Carmelaram Post, Bangalore, IN
Source
Journal of Pharmaceutical Research, Vol 15, No 3 (2016), Pagination: 101-104Abstract
Aim : The aim of case series is to describe the 3 Hemoglobin E ß-thalassemia cases, which are unique and requires special care and attention to diagnose/manage. Its natural history is little known, and also the reasons for their clinical diversity, or/and its management.
Presentation of case : 3 cases of transfusion dependent Hemoglobin E β -thalassemia major were included in the study. The patients reported similar complaints of weakness and delayed milestones. The patients were on regular red blood cell transfusion and iron chelation therapy from the age of 3 years. The beta-globin gene defects were defined in all the cases using similar techniques. Thalassemia mutation analysis by reverse clot blot testing showed a compound heterozygous for IVS 1-5 [G-C] and codon 26 [G-A] beta E mutation in the beta globin gene. Evaluation for iron overload showed severe cardiac iron deposit and severe hepatic iron deposit on MRI T2. During hospital stay, the patients received antibiotics and immune-suppressants in common.
Discussion & Conclusion : Patients are treated by lifelong blood transfusion every 15 to 30 days along with iron chelation therapy. Repetitive transfusions cause iron overload, with life-threatening complications, like such as cardiomyopathy, endocrine disorders, liver failures and, ultimately, premature death.Awareness, education and screening play the most important part in the prevention of life-threatening complications and control of thalassemia.
Keywords
Hb E/β Thalassemia, Transfusion Dependent, Hb E Mutation, Thalassemia Major.References
- Nadkarni A, GorakshakarA.C., LuC.Y., Krishnamoorthy R., Ghosh K, Roshan C, Mohanty D. Molecular Pathogenesis and Clinical Variability of â-Thalassemia Syndromes Among Indians. American Journal of Hematology.2001;68:75–80.
- Mujawar Q, Ukkali S, Malagi N N, ThobbiA N.Haemoglobin E beta-Thalassemia.A case report from Bijapur, South India. Al Ameen J Med Sci. 2009;2 (1):82 84.
- Dreuzy E, Bhukhai K, Leboulch P, Payen E. Current and future alternative therapies for beta-thalassemiamajor. Biomed J.2016;39(1):24-38.
- Olivieri NF, Pakbaz Z, Vichinsky E. Hb E/betathalassaemia: A common & clinically diverse disorder. Indian J Med Res, 2011;134, 522-531.
- Oliveri NF. Treatment strategies for hemoglobin E betathalassemia. Blood Rev.2012;26 (1):28-30.
- Galanello R, Raffaella O. Beta-thalassemia. Orphanet Journal of Rare Diseases.2010;5-11.